Digestible Indispensable Amino Acid Score

Digestible Indispensable Amino Acid Score (DIAAS) is a protein quality method proposed in March 2013 by the Food and Agriculture Organization to replace the current protein ranking standard, the Protein Digestibility Corrected Amino Acid Score (PDCAAS).

The DIAAS accounts for amino acid digestibility at the end of the small intestine, providing a more accurate measure of the amounts of amino acids absorbed by the body and the protein’s contribution to human amino acid and nitrogen requirements. This is in contrast to the PDCAAS, which is based on an estimate of digestibility over the total digestive tract. Values stated using this method generally overestimate the amount of amino acids absorbed.[1]

Reference pattern

Amino acid requirements were determined in two parts. The amino acid distribution of breast milk was used for the 0 to 6 month age range, and existing amino acid data was used for older ages after adjustment for digestibility. The reference amino acid requirements are presented below.[2]: 29 

Requirements by age (mg/g protein)
Amino acid0 to 6 months6 months to 3 yearsOver 3 years
Histidine212016
Isoleucine553230
Leucine966661
Lysine695748
Methionine + Cysteine (SAA)332723
Phenylalanine + Tyrosine (AAA)945241
Threonine443125
Tryptophan178.56.6
Valine554340

References
  1. "FAO proposes new protein quality measurement. March 2013". Archived from the original on 2017-05-19. Retrieved 2016-05-10.
  2. FAO (2013). Dietary protein quality evaluation in human nutrition (PDF). ISBN 978-92-5-107417-6. Retrieved 2021-10-10.
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