Integrator complex subunit 5

INTS5
Identifiers
Aliases	INTS5, INT5, KIAA1698, integrator complex subunit 5
External IDs	OMIM: 611349 MGI: 1923578 HomoloGene: 35303 GeneCards: INTS5
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	62,653,302 bp[1]
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)[2]
End	8,897,888 bp[2]
RNA expression pattern
	Top expressed in
	stomach; ; Right lobe of liver; ; left coronary artery; ; urinary bladder; ; gastrocnemius muscle; ; islet of Langerhans; ; fallopian tube; ; prefrontal cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	GO:0001948 protein binding;
Cellular component	integrator complex; integral component of membrane; membrane; nucleus; nucleoplasm; nuclear membrane; cytoplasm;
Biological process	snRNA processing; snRNA transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	80789
	109077
	ENSG00000185085
	ENSMUSG00000071652
	Q6P9B9
	Q8CHT3
	NM_030628
	NM_176843
	NP_085131
	NP_789813
	Wikidata
View/Edit Human	View/Edit Mouse

Integrator complex subunit 5 is a protein that in humans is encoded by the INTS5 gene. [5]

Function

The Integrator complex is a complex that associates with the C-terminal domain of RNA polymerase II large subunit. This complex is brought to U1 and U2 small nuclear RNA genes, where it is involved in the transcription and processing of their transcripts. The protein encoded by this gene represents a subunit of the Integrator complex.

References

GRCh38: Ensembl release 89: ENSG00000185085 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000071652 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Integrator complex subunit 5". Retrieved 2017-10-09.

Integrator complex subunit 5

Function

References

Further reading