Urolithin B

Urolithin B (UB)[1] is an urolithin, a type of phenolic compounds produced in the human gut after absorption of ellagitannins-containing food such as pomegranate,[2] strawberries, red raspberries, walnuts or oak-aged red wine.[3] Urolithin B is found in the urine in the form of urolithin B glucuronide.

Urolithin B
Names
Preferred IUPAC name
3-Hydroxy-6H-dibenzo[b,d]pyran-6-one
Other names
Uro-B
3-Hydroxyurolithin
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.236.446
UNII
  • InChI=1S/C13H8O3/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)16-12(10)7-8/h1-7,14H
    Key: WXUQMTRHPNOXBV-UHFFFAOYSA-N
  • C1=CC=C2C(=C1)C3=C(C=C(C=C3)O)OC2=O
Properties
C13H8O3
Molar mass 212.204 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

One of the producers of urolithin B, Cofttek, a Chinese pharmaceutical firm,[4] has been starting to mass produce urolithin B since early June 2021.[5]

See also

References
  1. "Urolithin A augments angiogenic pathways in skeletal muscle by bolstering NAD+ and SIRT1". Nature.com. Scientific Reports. 19 November 2020.
  2. Bialonska D, Kasimsetty SG, Khan SI, Ferreira D (11 November 2009). "Urolithins, intestinal microbial metabolites of Pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay". J Agric Food Chem. 57 (21): 10181–6. doi:10.1021/jf9025794. PMID 19824638.
  3. Cerdá, Begoña; Tomás-Barberán, Francisco A.; Espín, Juan Carlos (2005). "Metabolism of Antioxidant and Chemopreventive Ellagitannins from Strawberries, Raspberries, Walnuts, and Oak-Aged Wine in Humans: Identification of Biomarkers and Individual Variability". Journal of Agricultural and Food Chemistry. 53 (2): 227–235. doi:10.1021/jf049144d. PMID 15656654.
  4. "China fires back at U.S. allegations of lack of transparency". Associated Press. 14 February 2021.
  5. "What are the differences between Urolithin A and Urolithin B?". Yahoo News. 15 June 2021.


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