Only Murders in the Building

• Steve Martin as Charles-Haden Savage,[7] a semi-retired actor who was the star of the popular 1990s detective drama TV series Brazzos. He lives in 14C at the Arconia
• Martin Short as Oliver Putnam,[7] a financially struggling Broadway director who spawns the idea of the podcast, and becomes its director. He lives in 10D at the Arconia
• Selena Gomez as Mabel Mora,[7] a young woman who lives in 12E at the Arconia, a refurnished unit that she is renovating for her aunt, and who was friends with Tim Kono (the murder victim) years ago
• Aaron Dominguez as Oscar, a friend of Mabel and Tim who was wrongly convicted of the murder of their friend Zoe ten years ago and was discharged from prison recently
• Amy Ryan as Jan, a professional bassoonist who also lives in the Arconia and starts dating Charles
• Cara Delevingne as Alice (season 2)[8]

• Vanessa Aspillaga as Ursula, the building manager of Arconia
• Julian Cihi as Tim Kono, a resident living in 9A at the Arconia who dies in the first episode. The mysterious circumstances surrounding Tim's death spurs Charles, Oliver, and Mabel to do their own investigation.
• Tina Fey as Cinda Canning, the host of a true crime podcast called All Is Not OK in Oklahoma[9]
• Ryan Broussard as Will, Oliver's son
• Jackie Hoffman as Uma Heller, a resident of Arconia
• Maulik Pancholy as Arnav, a resident of Arconia, Charles' next-door neighbor
• Jayne Houdyshell as Bunny, the iron-fisted lead board member and resident of Arconia
• Da'Vine Joy Randolph as Detective Williams, a detective on the Kono murder who initially closed the case but becomes interested once again when her wife starts listening to the podcast
• Teddy Coluca as Lester, the doorman of Arconia
• James Caverly as Theo Dimas, a resident of Arconia and Teddy Dimas' son
• Michael Cyril Creighton as Howard Morris, a resident of Arconia and cat lover, whose cat Evelyn died the same night as Tim Kono
• Zainab Jah as Ndidi Idoko, a resident of Arconia, Tim Kono's next-door neighbor who looks forward to annexing his apartment
• Russell G. Jones as Dr. Grover Stanley, a resident of Arconia who is a therapist
• Olivia Reis as Zoe Cassidy, a friend of Mabel, Oscar and Tim who all were part of the four-member friend group called "Hardy Boys". She fell to death from the rooftop of Arconia 10 years earlier, and her boyfriend Oscar is wrongly accused of her murder.
• Jeena Yi as Amy Huang, a resident of Arconia
• Nathan Lane as Teddy Dimas, a resident of Arconia, deli chain owner, and old friend and patron of Oliver's, who agrees to sponsor the podcast

• Sting as a fictionalized version of himself, a resident of Arconia[10]
• Adriane Lenox as Roberta, Oliver's ex-wife
• Anthony Ruiz as Jose Torres, who is Oscar's father and the superintendent of Arconia
• Adina Verson as Poppy, a determined assistant of Cinda
• Roy Wood Jr. and Jacob Ming-Trent as Vaughn and Lucian
• Jimmy Fallon as himself
• Mandy Gonzalez as Silvia Mora, Mabel's mother
• Jaboukie Young-White, Daniel Oreskes, Ali Stroker, and Orson Hong as Sam, Marv, Paulette, and Grant, who are Only Murders in the Building podcast enthusiastic fans
• Jane Lynch as Sazz Pataki, Charles' long-time friend and his former stunt double

In January 2020, it was announced Steve Martin and Martin Short would star in an untitled Hulu series, created by Steve Martin and John Hoffman, with Martin, Short, and Hoffman as executive producers, alongside Dan Fogelman, with 20th Television serving as the studio.[13] On September 14, 2021, Hulu renewed the series for a second season.[6]

Alongside the initial announcement, it was announced Martin and Short would star in the series.[13] In August 2020, Selena Gomez joined the cast and also serves as an executive producer.[14] In November 2020, Aaron Dominguez joined the cast in a series regular role.[15] In January 2021, Amy Ryan joined the cast in a series regular role.[16] That same month, Nathan Lane joined the cast in a recurring role.[17] On December 1, 2021, it was reported that Cara Delevingne joined the cast as a new series regular for the second season.[8]

Principal photography began on December 3, 2020, in New York City,[18] and concluded in April 2021.[19] The Belnord was used for exterior shots as the fictional Arconia Building.[20] Filming for the second season began on December 1, 2021.[21]

A digital album for the score was released on August 27, 2021, four days before the series' debut.[22]

All music is composed by Siddhartha Khosla.

On September 3, 2021, it was reported that Only Murders in the Building set a record for the most-watched comedy premiere in Hulu history.[24]

On October 28, 2021, Hulu Originals president Craig Erwich revealed in an interview with Vulture that the show had become the most-watched comedy ever on Hulu "by a good measure." In the same article, Vulture reported that, according to Parrot Analytics, the show went from having about 16 times the audience demand in the U.S. as an average show back when it debuted on August 31, to generating 37 times typical demand by the time the season-one finale dropped on October 19. This meant that the day after the finale the show ranked as high as 14th on the list of most in-demand shows in the U.S. and signaled a "massive" 135 percent growth rate that according to Erwich is mainly to be attributed to word of mouth.[25]

The performances of the main cast, namely (left to right) Steve Martin, Martin Short, and Selena Gomez, have received critical acclaim.

The review aggregator website Rotten Tomatoes reported a 100% approval rating with an average rating of 8.00/10, based on 96 critic reviews. The website's critics consensus reads, "Only Murders in the Building's silly approach to true crime obsessives is at once hilarious and insightful, thanks in large part to its extremely charming central trio."[26] Metacritic gave the first season a weighted average score of 76 out of 100 based on 34 critic reviews, indicating "generally favorable reviews".[27]

Kristen Baldwin of Entertainment Weekly gave the series a B and wrote, "Only Murders delivers above-average laughs, a clever mystery, and a starry cast. But it's hard to shake the feeling that the show missed an opportunity to be something special."[28] Reviewing the series for Rolling Stone, Alan Sepinwall gave a rating of four and a half out of five stars and said, "The series soon turns out to be—like The Princess Bride, Galaxy Quest, or Jane the Virgin—that rare and wonderful thing: the parody that also offers a great example of the genuine article."[29]