Saath Nibhaana Saathiya 2

• Sneha Jain as Gehna Desai – Desais' former maid; Kusum’s elder daughter; Swara's elder sister; Anant's wife (2020–present)
• Harsh Nagar as Anant Desai – Jamuna and Praful's son; Hiral, Pankaj, Chetan and Tia's brother; Gehna's husband (2020–present)
• Akanksha Juneja as Kanak Dholakia (Formerly Desai) – Jigna's daughter; Pankaj's former wife (2020–present)
• Rashmi Gupta as Swara Desai – Kusum's younger daughter; Gehna's sister; Pankaj's second wife (2021–present)

• Aliraza Namdar as Praful Desai – Paresh, Kokila and Jigna's brother; Jamuna's husband; Pankaj, Hiral, Chetan, Anant and Tia's father; Piyush, Sachi and Tannu's grandfather (2020–present)
• Anuradha Kanabar Namdar as Jamuna Desai – Hansa's sister; Praful's wife; Kokila’s Sister in Law; Pankaj, Hiral, Chetan, Anant and Tia's mother; Piyush, Sachi and Tannu's grandmother (2020–present)
• Hitesh Dave as Paresh Desai – Praful's brother (2021–present)
• Nadia Himani as Hema Majethia Desai – Bhavani and Dashrath's daughter; Sagar's sister; Chetan's wife; Piyush and Sachi's mother (2020–present)
• Prakash V. Wagela as Chetan Desai – Jamuna and Praful's second son; Pankaj, Hiral, Anant and Tia's brother; Hema's husband; Piyush and Sachi's father (2020–present)
• Jay Pathak as Pankaj Desai – Jamuna and Praful's eldest son; Hiral, Chetan, Anant and Tia's brother; Kanak's former husband; Swara's husband (2020–present)
• Vaishali Thakkar as Kusum – Swara and Gehna's mother (2021–present)
• Manas Adhiya as Sagar Majethia – Bhavani and Dashrath's son; Hema's brother; Suman's husband; Kanak's accompliance (2020–present)
• Hardika Joshi as Hiral Desai Parekh – Jamuna and Praful's elder daughter; Pankaj, Chetan, Anant and Tia's sister; Sapan's wife; Tannu's mother (2020–present)
• Ankur Panchal as Sapan Parekh – Hiral's husband; Tannu's father (2020–present)
• Jinal Jain as Tia Desai – Jamuna and Praful's younger daughter; Pankaj, Hiral, Chetan and Anant's sister; Krishna's love interest (2020–present)
• Sanket Chouske as Krishna Rawat – Gehna's childhood friend; Tia's fiancé (2021–present)
• Ashar Khan as Piyush Desai – Hema and Chetan's son; Saachi's brother (2020-2021)
• Aarifa Siddiqui as Saachi Desai – Hema and Chetan's daughter; Piyush's sister (2020-2021)
• Prachi Bisht as Tanushree "Tanu" Parekh – Hiral and Sapan's daughter (2020)
• Krutika Desai as Radhika Virani – Anant's former fiancée; Vineet's former wife (2020–2021)
• Sachin Parikh as Vineet Virani – Radhika's former husband (2021)
• Khyati Vaghela as Mayuri Tripathi – Hansa's daughter-in-law. (2021)
• Leela Tejwani as Hansa Tripathi – Jamuna's sister. (2021)
• Himanshu Gokani as Dashrath Majethia – Bhavani's husband; Hema and Sagar's father; Kanak's accomplice. (2021)
• Durga Mahlotra as Bhavani Majethia – Dashrath's wife; Hema and Sagar's mother. (2021)
• Mohini Singh as Suman Majethia – Sagar's wife (2021)
• Subhalaxmi Das as Jigna Dholakia – Kanak's mother and accomplice. (2021)
• Deepika Agarwal as Mona – Kanak's fashion expert. (2021)
• Sudhir Jain as Amrish Mehta – An arrogant model advisor. (2021)
• Riya Mehta as Shivangi Mehta – Gehna's moral supporter and a model advisor. (2021)
• Sikandar Kharbanda as Professor Kumar – Gehna's professor; Sagar's boss (2021)
• Anshul Bamni as Dr. Srivastava: Senior Officer of Anant's secret mission (2021)
• Pratibha Tiwari as Sia Srivastava – Srivastava's sister (2021)

The original cast from season one made cameo appearances in the series to introduce the new leads, cast as well as to promote the storyline.

• Devoleena Bhattacharjee as Gopi Kapadia Modi – Jayantilal and Madhu's elder daughter; Radha's sister; Rashi's cousin; Ahem and Jaggi's wife; Meera, Vidya and Ramakant's mother. (2020)
• Rupal Patel as Kokila Desai Modi – Revati's elder daughter; Jigna, Praful and Paresh's sister; Parag's wife; Ahem and Kinjal's mother; Jaggi's step-mother. She is the strict and dominating matriarch of the Modi family. (2020)
• Mohammad Nazim as
  • Ahem Modi – Parag and Kokila's son; Kinjal's brother; Jaggi's twin half-brother; Gopi's first husband; Meera, Vidya and Ramakant's father. He is shown to be dead but he survived and only lost his memory. He was saved and taken care by Gehna. Later, he regains his memory and reunites with his family. (2020)
  • Jaggi Modi – Urvashi and Parag's son; Kokila's step-son; Ahem and Kinjal's half-brother; Gopi's second husband. He married Gopi after Ahem's supposed demise. (2020)
• Manish Arora as Parag Modi – Janko and Tolaram's younger son; Chirag's brother; Kokila's husband; Ahem, Jaggi and Kinjal's father. (2020)
• Swati Shah as Hetal Modi – Chirag's wife; Kokila's cousin; Jigar's mother; Rashi’s Mother in law. She is sweet and sensible, and always thinks about the welfare of Modi's. (2020)
• Vandana Vithlani as Urmila Shah – Jitu's wife; Rashi's mother; Gopi, Radha, Dhaval and Paridhi's aunt.(2020)

In July 2020, Devoleena Bhattacharjee signed the contract for the new season with the production under plans since a year before.[5][6] Admist this, the rap by Yashraj Mukhate released on 21 August 2020 went viral and the re-run of the series Saath Nibhaana Saathiya during the Coronavirus lockdown was garnering good ratings which made the makers to immediately start production of the new season of the series and released the first promo on 31 August 2020 featuring Bhattacharjee reprising her role of Gopi Modi while the casting was not even started.[7]

On 26 May 2021, Shoonya Square Productions announced that they will be producing a reboot version of Saath Nibhaana Saathiya on Star Plus's Sister channel Star Bharat with similar cast figures like Giaa Manek, Mohammad Nazim, Rupal Patel and Vandana Vithlani reprising their roles.[8][9] Along with these actors, they will be several new characters with a different storyline but the same concept of a Gujarati joint family.[10] In early July 2021 the title was finalized as Tera Mera Saath Rahe.[11] The reboot version started broadcasting from 16 August 2021.

Based on the backdrop of Surat, in Gujarat, the series is completely filmed at the Ramdev Studio in Naigaon.[12]

On 14 April 2021, shooting halted due to COVID-19 precautions set by Uddhav Thackeray, the chief minister of Maharashtra. On 18 and 19 April, the entire team of Saath Nibhaana Saathiya 2 shifted their base to Agra and continued shooting there till early June.[13]

The first promo of the series was released on 31 August 2020 featuring Bhattacharjee reprising her role of Gopi from the former season.[14] On 1 October 2020, a new promo revealed Bhattacharjee playing Gopi introduced Sneha Jain and Harsh Nagar as the lead characters, Gehna and Anant.[15] In the next promo released on 14 October 2020, Rupal Patel was shown reprising her role as Kokila Modi. The series premiered on 19 October 2020 at 9.00 pm time slot on StarPlus.[16]

The main plot of the series is taken from Star Jalsha's Bengali series Ke Apon Ke Por, even though some parts of the story are removed from the plot of Saath Nibhaana Saathiya 2. The extension of the first season's story is shown as the sub plot in this season merged with the main story, featuring Devoleena Bhattacharjee, Mohammad Nazim, Rupal Patel, Swati Shah, Vandana Vithlani and Manish Arora from the former series, only during the initial 30 episodes of the series.

With the release of first promo, Devoleena Bhattacharjee, Rupal Patel and Mohammad Nazim were confirmed reprising their roles of Gopi, Kokila and Ahem Modi/Jaggi Modi (double role).[17][18][19] Vishal Singh confirmed being approached for reprising their role of Jigar Modi, but finally declined it.[20] Rucha Hasabnis declined to reprise her role as Rashi Modi in the new season, as her character had died in the former season and that she did not wish to perform a role in a typical family drama.[21]

On 13 September 2020, Sneha Jain and Harsh Nagar were confirmed to reprise their lead roles as Gehna and Anant.[22] Soon, with the first look of the series, Vandana Vittlanee, Swati Shah and Manish Arora were confirmed reprising their roles of Urmila Shah, Hetal Modi and Parag Modi from the former season.[23] Besides the former season's cast and the leads, Jay Pathak, Akanksha Juneja, Nadia Himani, Prakash Vaghela, Aliraza Namdar and Anuradha Kanabar were cast to perform the recurring roles of the show.

Soon, it was revealed that the cast from the first season were only shooting for a few episodes in order to introduce the new leads of the show. In mid-November 2020, the entire cast of the former season quit the series due to the promoter's demand on having only one track and that the show completely focused on the original show, Ke Apon Ke Por.[24]

In June 2021, lead actress, Akanksha Juneja took a break from the sets. During her absence, the show focused on Hema Desai aka Nadia Himani. The show also changed the storyline slightly due to Juneja's absence and introduced a new character, Krishna, played by Sanket Chouske.[25]

The Times of India reviewed, "Ahem's mysterious presence in Gopi's life, Kokila's sass and injustice towards Gehna will keep you hooked."[26] India Today criticized the launch of the new season as unnecessary and on the other hand criticizing the former season saying, "During the course of seven years, the show took three major leaps – eight years, 10 years and four years. That is 22 years in total. Yet they've something left to tell the audience? Needless to say, how the show turned to be ridiculous on several occasions. Saath Nibhaana Saathiya tried to be progressive but the show was regressive to the core."[27][28][29]